Objective research and reviews to aid investing decisions
Do long-term investors in small-capitalization firms outperform? Is the size effect simply a manifestation of data snooping or defective statistical methodologies? In his January 2006 paper entitled "Is Size Dead? A Review of the Size Effect in Equity Returns", Mathijs van Dijk reviews the international evidence for the size effect and synthesizes the debate on its theoretical validity and empirical persistence. He concludes that:
The following chart, taken from the paper, shows the difference in annual, market-weighted returns between the 20% of all NYSE, AMEX and Nasdaq stocks with the smallest market capitalization and the 20% with the largest market capitalization over the period 1927-2004. These returns are not risk-adjusted. The chart shows that the size effect is not consistent.

The next chart, also from the paper, shows the return differential from the chart above by calendar month. The chart shows that most of the size effect appears in January.

In summary, the empirical evidence for the size effect is superficially consistent, but frail at closer inspection. The size effect is not "dead," but it is ailing.
To us, the greater weight of evidence still favors small stocks.
For related research, see Blog Synthesis: The Size Effect.